The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses
نویسندگان
چکیده
منابع مشابه
The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses.
Pathogen-associated molecular patterns decisively influence antiviral immune responses, whereas the contribution of endogenous signals of tissue damage, also known as damage-associated molecular patterns or alarmins, remains ill defined. We show that interleukin-33 (IL-33), an alarmin released from necrotic cells, is necessary for potent CD8(+) T cell (CTL) responses to replicating, prototypic ...
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ژورنال
عنوان ژورنال: PEDIATRICS
سال: 2012
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.2012-2183qq